Amevive® (alefacept) is a prescription biologic medication for adults with moderate-to-severe chronic plaque psoriasis who are
candidates for systemic therapy or phototherapy.[1] Your doctor gives you an injection of Amevive
once a week for 12 weeks, then you get a
break from therapy for 12 weeks—or more.[1-3] For some people who have responded, treatment breaks have
lasted 4 months…or longer. When you are taking Amevive, a blood test will be done
every 2 weeks to check your T-cell levels.[1] T cells are a type of white blood cell that fight disease.
Explore Amevive.com. This site will help you understand Amevive, how to get started, and also how you may be able to get reimbursement
support throughout treatment.
Sign up for the Amevive Treatment Assistant
The Amevive Treatment Assistant is a step-by-step guide that walks you through your treatment experience. Each of the 5 Amevive Action Steps
covers different stages of your treatment. You’ll receive advice, plus tools such as a treatment calendar and a daily symptom tracker, so you can
record your symptoms and share them with your doctor as you proceed with treatment. You’ll also have access to real patient stories about Amevive.
Don’t go through treatment alone…sign up today!
Learn about Amevive
Learn more about Amevive—a prescription medication that may help you manage your psoriasis and give you a break from therapy.
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How to get started on Amevive
Find out which available program can help you get started on Amevive.
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Instant savings opportunity
See how you may be able to save instantly on Amevive.
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References
- 1. Amevive® (alefacept) prescribing information, Astellas Pharma US, Inc.
- 2. Lebwohl M, Christophers E, Langley R, et al. An international, randomized, double-blind, placebo-controlled phase 3 trial of
intramuscular alefacept in patients with chronic plaque psoriasis. Arch Dermatol. 2003;139:719-727.
- 3. Data on file, Astellas Pharma US, Inc.
Amevive is approved for the treatment of moderate to severe chronic plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.
Important Safety Information
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Amevive reduces the number of certain T cells. That is part of how it is thought to treat psoriasis. This reduction could increase the
possibility of getting an infection or cancer. Before taking Amevive, be sure to tell your doctor if you have had a serious infection or
cancer. Amevive should not be taken if you are HIV positive.
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Because Amevive reduces the number of T cells, you should have a blood test every 2 weeks during the dosing period to check your T-cell
levels. If your T-cell levels are too low, your doctor will check your blood weekly and will either postpone or stop treatment with Amevive.
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Some patients who received Amevive in clinical studies were found to have cancers. Most of these cases were skin cancers. There were also
other types of cancer and lymphomas. Some patients developed serious infections, including wound infections and pneumonia.
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During and after taking Amevive, if you notice anything unusual about your health or any signs of infections such
as swollen glands, fever, or chills, notify your doctor right away.
-
Amevive should not be taken if you are known to be allergic to Amevive or any of its components, since serious
allergic reactions such as hives, with or without swelling of the mouth and tongue, have been seen.
-
Some patients treated with Amevive have had serious liver injury. If your skin or the whites of your eyes become yellow, if you start to
bruise easily, or if you have persistent loss of appetite or vomiting, you should call your doctor right away.
-
Commonly reported side effects that occurred in clinical studies with Amevive included sore throat, dizziness, cough, nausea, itching,
muscle aches, chills, injection site reactions, and accidental injury.
If you become pregnant during treatment with Amevive, tell your doctor and consider enrolling in the Pregnancy Registry by calling 1-866-834-7223.
Information collected in this program is kept confidential.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit
fda.gov/medwatch or
call 1-800-FDA-1088.
Please see the full prescribing information and talk to your
doctor for more information.